Zejtlin studied at the Institute of Art in Odessa and at the Institute of Artistic Perfection in Moscow. In 1945 he became a member of Moscow's Artists Union. In 1978 he was awarded with the title of Meritorious Artist of the Republic of Russia.
He participated in several exhibitions of figurative soviet art, both in Europe and America. His works can be found in the Tret'jakov Gallery in Moscow, the Russian Museum in St. Petersburg and in numerous private collections in Europe, America and Japan. Over the past fifty years, he has been considered a leading figure of Postwar Russian art.